Sharon Kirkey , Canwest News ServicePublished: Tuesday, August 19, 2008
A leading Canadian researcher is warning people about taking their daily dose of prescription pills with orange or apple juice - nearly 20 years after his earlier caution about grapefruit juice prompted sticker warnings on drug vials.
David Bailey and colleagues announced to a startled - and skeptical - medical world in 1991 that grapefruit juice can boost the amount of certain drugs absorbed into the bloodstream two- to threefold, turning normal doses into potentially toxic overdoses. Today, nearly 50 drugs carry labels warning about the so-called Grapefruit Juice Effect.
Now, in another surprise discovery, Bailey is reporting that grapefruit juice - as well as orange and apple juice - also appears to do the opposite by substantially lowering the absorption of certain other drugs, including certain antibiotics and drugs used to treat high blood pressure and heart disease
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